There is a big difference between leukocyte and platelet-rich fibrin (LPRF) and platelets rich in growth factors (PRGF) in results and efficacy. LPRF came out as an alternative to PRGF because the technique for collecting and processing the material was easier and took less time. A recent article came out showing that LPRF was no more effective than blood clot in the healing of jawbone defects. (J Oral Maxillofac Surg 79:575-584, 2021).

I have been using PRGF for over 10 years. PRGF showed a quantum leap in the healing of jaw defects as a part of bone grafting techniques. There are surprisingly still relatively few surgeons taking advantage of this process. The main reasons are cost and time. If you want excellence – go with PRGF.

These other techniques such as PRF or LPRF result in a “mixing of cells” and lack the specific concentration of growth factors which gives us so much better results in our bone grafting and implant procedures. I am happy to answer questions regarding these techniques. Our goals are to provide the best care, in a cost effective way, without sacrificing results. We have a great track record with PRGF and I am proud of it. Do your research. Be aware that these processes have similar names and very often offices are advertising the use of these materials without using the proper techniques.